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An in vitro study demonstrated that CRP upregulates M-CSF release from human aortic endothelial cells and increases macrophage proliferation, and these effects appeared to be mediated through the activation of NF-B via CD32 and CD64, thus providing further evidence for its proatherogenic role [149]
Kojima K, Kornblau SM, Ruvolo V, Duvvuri S, Davis RE, Zhang M, Wang Z, Coombes KR, Zhang N, Qiu YH, Burks JK, Ruvolo P, Shacham S, Kauffman M, Andreeff M
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Molfino, A., Cascino, A., Conte, C., Ramaccini, C., Rossi, Fanelli F., and Laviano, A
