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Description
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Gut elimination of uric acid, which couples transport into the small intestinal lumen and colonic bacterial urate oxidation by uricase, normally removes ~200 mg of uric acid daily in humans ( Figure 1 - 3A ), but this elimination pathway has limited potential for adaptive increases in capacity beyond ~100 mg more daily
10.1002/prot.10286 54 LuY
Zhao and Zhao, 2013)
