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As the male population has a decrease in sperm count and a dramatic increase in infertility, observations suggest that testicular disease may be an important component of male infertility aetiology of promoting epigenetic transgenerational inheritance (Reference Sadler-Riggleman, Klukovich and Nilsson36)

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J Urol (2009) 181:74151

Similarly, surveys and research trials report that many individuals experience slight to moderate benefits with few side effects