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Pushing a patient past their tolerability threshold often leads to protocol abandonment
CD38 is functionally dependent on the TCR/CD3 complex in human t cells
(1973b)
2000), several studies have demonstrated good concordance of the assay with the in vivo transgenic rodent (TGR) somatic mutation assay and also high sensitivity of 92.1% (35 out of 38 chemicals correctly identified) for detecting human IARC group 1 and Group 2A carcinogens, comparable to the TGR assay with 90.3% (Kirkland et al
