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is subject to confounding by hospital (treatment highly dependent on the hospital, different SOC/ICU transfer practices, not included in PS), immortal time (only partly addressed in sensitivity analysis), co-treatment differences, calendar-time (SOC evolved rapidly early in the pandemic), binary coding for age (age 65 despite steep age-risk gradient), residual imbalance (variables dropped from PS), a composite outcome dependent on hospital triage/capacity, and other factors

[PMC free article: PMC4246417] [PubMed: 25424739] 46

Location and Transportation Centrally located in the Uptown neighborhood near UPMC Mercy, Duquesne University, and the Monongahela River, Pyramid Pittsburgh Outpatient Treatment Center provides access to residents throughout Pittsburgh

Therefore, understanding the cellular and molecular mechanisms that contribute to chronic radiodermatitis onset and progression is essential for developing targeted therapies that can prevent or reduce the severity of fibrotic changes, ultimately aiming to preserve patient quality of life and improve cancer care post-radiotherapy