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Description
Several potential therapeutic targets related to cholesterol ester metabolism have been identified, including: Acyl-CoA:Cholesterol Acyltransferase (ACAT) : Inhibitors of ACAT, such as avasimibe and pactimibe, reduce cholesterol ester synthesis and intracellular lipid accumulation, offering potential benefits for reducing atherosclerosis progression and improving lipid profiles
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TRPC6 is a glomerular slit diaphragm-associated channel required for normal renal function

Some studies also report headaches, fatigue and flushing
