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It quiets food noise (the constant low-level thoughts about eating), slows gastric emptying so meals stay satisfying for longer, and reduces post-meal blood sugar spikes that drive cravings

[DOI] [PMC free article] [PubMed] [Google Scholar] 123.Vanduchova A., Anzenbacher P., Anzenbacherova E

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To determine the liver protection by rectal ozone insufflation in patients with RA, a controlled clinical trial with 100 patients was performed: n = 50 as MTX-group (MTX + Ibuprophen + folic acid) and n = 50 as ozone group receiving the same medication + rectal ozone insufflations as described above and in detail in [26,27,28]