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confirmed an increase in skin thickness in the range of the epidermis and dermis, improved skin hydration, a significant smoothing of the skin by stimulating collagen synthesis, increased skin elasticity, a significant improvement in skin contrast and an increased production of collagen I [18,19]

PLoS ONE 7 , e35421 (2012)

For anything causing significant discomfort, functional impairment, or progressive worsening, adjustment or discontinuation is prudent

In a randomized, double-blind, two-arm, placebo-controlled study (n=60) conducted in the Thai population, the effect of orally administered glutathione (500 mg/day) on the melanin index of the skin was investigated in sixty healthy individuals