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Fatty Acid Substrate Specificities of Human Prostaglandin-Endoperoxide H Synthase-1 and 2: FORMATION OF 12-HYDROXY-(9Z,13E/Z,15Z)-OCTADECATRIENOIC ACIDS FROM -LINOLENIC ACID
Also, low bioavailability and rapid metabolism prevent the achievement of the pharmacologically relevant concentrations of the pharmacologically active compounds in preclinical studies
doi: 10.1016/j.jtemb.2014.11.009 43 BelaidiAAGunnAPWongBXAytonSAppukuttanATRobertsBRet al
