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Teratogenicity VPA's teratogenic effects are thought to begin in the earliest stages of organogenesis when the closure of the neural tube is extremely sensitive to its metabolite (Brotzmann et al., 2021)
doi: 10.1016/j.molcel.2016.03.036
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In atherosclerotic lesions, monocytes, macrophages, endothelial cells, vascular smooth muscle cells, and platelets all show iron overload, and their involvement promotes the progression of atherosclerosis (Vinchi et al., 2014)
