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Description
Some of the beneficial metabolic actions of polyphenols are mediated by their ability to activate SIRT1 (235), as resveratrol, a polyphenolic substance, activated SIRT1, leading to the modulation of LKB1/AMPK-signaling axis (91)

However, this low efficiency of infection was sufficient to increase lifespan of male mice to 16.6 weeks and improve motor impairments, but it did not have any effect on respiratory symptoms

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Pisoschi and Pop, 2015)
