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These two residues represent a known pyridoxal phosphate-binding site in E.coli GAD (H275 and K276) that is likely conserved in mammalian GAD65
The enzymes of glutathione synthesis: Gamma-glutamylcysteine synthetase

Li et al., 2018) and its drug activity in the treatment of arthritis and osteoporosis were also found (Watanabe et al., 2015
