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doi: 10.3389/fmicb.2020.517797 263 LeeKKimNShimJOKimGH
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Although it is known that the promoter regions of the genes encoding GLCL and GSTs possess binding sites for such transcriptional regulators as NF- B, AP-1, AP-2, SP-1, and others [192194], most attention has been concentrated on the Nrf2/Keap1 system [160, 195]
Apparent differences in graying patterns across populations and the potential link between premature graying and broader health issues highlight the need for a shift in research priorities
