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Ahmed and Kumar [39] evaluated the antidiabetic properties of hydroalcoholic extracts from CA leaves, which demonstrated significant effects by inhibiting the activity of alpha amylase and glucosidase enzymes, enhancing glucose absorption in peripheral tissues, and potentially imitating the action of insulin

Kim WS, Rahmanto AS, Kamili A, Rye KA, Guillemin GJ, Gelissen IC, Jessup W, Hill AF, Garner B

The serin-protease tPA has been shown to disrupt the BBB integrity and favor monocyte infiltration in mouse models of multiple sclerosis (Table 4) [148]

These appeared as having modulatory effects on NO-system (NO-release, NOS-inhibition, NO-over-stimulation all affected), controlling vasomotor tone and the activation of the Src-Caveolin-1-eNOS pathway and modulatory effects on the prostaglandins system (BPC 157 counteracted NSAIDs toxicity, counteracted bleeding, thrombocytopenia, and in particular, leaky gut syndrome)