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Description
Promising in animals, limited in humans
There is no dependency
In BV2 and primary glial cultures, low-dose 2DG reversed LPS-induced metabolic reprogramming, restoring OXPHOS, reducing mitochondrial fragmentation, and enhancing biogenesis
Although no eraser enzyme highly specific for lactylation modification has been identified to date, existing evidence suggests that deacetylases possess the potential to remove such modifications (104)
