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1 A dedicated human safety and tolerability evaluation supported an acceptable short-term profile at the doses tested, 8 and later characterization framed the ingredient as having a favorable safety and metabolism profile in the sponsors view

The compound appeared to reduce markers of hepatocellular inflammation and cell death in treated animals compared to controls

Initial results from the northstar study (HGB-204): a phase 1/2 study of gene therapy for -thalassemia major via transplantation of autologous hematopoietic stem cells transduced ex vivo with a lentiviral A-T87Q-globin vector (LentiGlobin BB305 drug product) [abstract] Blood

Compounded semaglutide is different from FDA-approved semaglutide and presents risks with its quality, safety, and dosing