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Akkermansia relative abundance was significantly higher in the vehicle-treated group switched from WD to LD compared to both the WD and LD control groups (Fig

2.1.1.1 All- trans retinoic acid (ATRA) CD38 expression can be modulated both in vitro and in vivo through the nuclear retinoic acid receptor ( in vivo use, has proven effective in enhancing CD38 levels in several ex vivo myeloma cell preparations, leading to improved efficacy of therapeutic antibodies ( in vivo efficacy in combination with Daratumumab was called into question in a clinical trial involving relapsed/refractory (RR) MM patients

After incubating in DMEM containing 1% FBS overnight to induce synchronization, the VSMCs were cultured with Ang II for 3 days