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Although oxidative stress markers were not assessed in the present study, it is plausible that the behavioral and biochemical benefits observedincluding reduced corticosterone levels and elevated BDNF expressionmay partly result from redox homeostasis improvements

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Response varies: early sensory symptoms like tingling often improve within weeks, whilst cognitive symptoms may take several months

31 , 33 , 34 mTORC1 is a protein complex that senses the availability of nutrients, growth Factors, and the presence of cellular stresses to coordinately regulate multiple physiological cellular processes like cell growth, proliferation, autophagy, organelle biogenesis, and Wnt signaling