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Excess Fe 2+ can donate electrons to H 2 O 2 and O 2 , resulting in substantial production of O 2 and OH free radicals which may cause lipid peroxidation of neuronal membranes as well as accelerated generation of guanidine compounds in the brain, ultimately leading to epileptic conditions (51)

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125 WuHTangXKimHJJalaliSPritchettJCVillasboasJCet al

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