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Data availability The BioProject PRJNA1290859 and associated SRA metadata are available [ All data are included in the Supplementary Information or available from the authors, as are unique reagents used in this Article

Clinical studies have demonstrated that targeted supplementation with NAC (often alongside glycine) can fully correct intracellular glutathione deficiencies, significantly reducing markers of oxidative lipid damage

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doi:10.1053/jhep.2002.33995 Nagelkerke JF, van de Water B, Twiss IM, Zoetewey JP, de Bont HJ, Dogterom P, Mulder GJ (1991) Role of microtubuli in secretion of very-low-density lipoprotein in isolated rat hepatocytes: early effects of thiol reagents