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In one small study, men who received glutathione before they exercised performed better, felt less fatigued and had lower levels of lactic acid in their blood
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In contrast, GSTP1 promotes ER stress-induced apoptosis in liver cancer by glutathionylating SERCA, thereby inhibiting pro-survival MAPK8 signaling 50
The latter is non-toxic, and the former is both mutagenic and carcinogenic and its presence can lead to a variety of symptoms including headache, tachycardia, nausea, and flushing of the skin, which can be used as an indicator of alcohol intolerance
