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While GLP-1 drugs like semaglutide or tirzepatide boost insulin secretion and reduce glucagon, cagrilintide primarily slows gastric emptying and suppresses appetite via amylin receptors

10.1038/s41586-024-07516-8 [DOI] [PMC free article] [PubMed] [Google Scholar] Camille C., Goff Ocane L., Frdric S., Vasseur F., Tanou M., Nguyen C., et al

Also, it is possible to measure melatonin in saliva, during the evening before sleep and this approach has been frequently used

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