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Despite the small size of the tri- and tetrapeptides, a property ultimately necessary for BBB permeability, these molecules were metabolically unstable and likely too hydrophilic to breach the BBB
doi: 10.1111/j.1365-2265.1995.tb02929.x 103 RaunKHansenBSJohansenNLThogersenHMadsenKAnkersenMet al
