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In one study, a decreased proportion of CD8 + T cells expressing CD107a, a marker of degranulation, in response to the N peptide pool stimulation, and a faster decline in the frequency of N-specific interferon--producing CD8 + T cells were observed in patients with LC after 4 months of COVID-19 onset [187]

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Moreover, this glucose control intervention increased the risk of hypoglycemic episodes (73)

High doses are more likely to produce side effects
