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Mediation analyses were additionally performed to explore the potential role of TMAO as a mediator of the association between choline and its related metabolites and NAFLD risk

Microbiome 5 (1), 54

In addition, luteolin downregulated the expression of C/EBP-, PPAR and SREBP1-c and increased the expression of pACC and pAMPK, preventing adipogenesis and alleviating metabolic disorders

The pesticide CYP can also lower LH, FSH, and TH levels, possibly by increasing oxidative stress and interfering with antioxidant enzyme synthesis and activity
