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Since most glucose-dependent insulinotropic polypeptide (GIP) receptor: glucagon-like peptide- 1 receptor (GLP- 1) receptor: glucagon receptor triagonists compete in efficacy with bariatric surgery, the success of these agents in preclinical models and clinical trials suggests a bright future for multi-agonists in the treatment of metabolic diseases

Our results demonstrate that MT enhances cell viability, ATP production, mitochondrial membrane potential, and respiration in both healthy and tau-mutant SH-SY5Y cells

Keatings lab spent many years designing peptides that would bind to the section of Mcl-1 involved in this interaction but not to other members of the protein family

doi: 10.3390/ijms24021043 78 SuS-CHsinC-HLuY-TChuangC-YHoY-TYehF-Let al