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The structure of these receptors allows for the modulation of inhibitory signaling by various pharmacological agents

W., and Rathfelder, E

Supporting evidence: Flattened diurnal slopes, attenuated cortisol awakening response, eveningpredominant DHEAS, and paradoxical elevations of salivary sex steroids under low cortisol/DHEAS conditions illustrate how chronic inflammation reprograms endocrine networks

Borenfreund E, Puerner JA
