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The prevalence of CD in the population is increasing, and specific environmental factors are associated with its development (12)

European Association of Urology guidelines on male infertility: the 2012 update

10.1016/j.jpsychires.2014.02.005 [DOI] [PubMed] [Google Scholar] 7.Nasca C, Bigio B, Lee FS, Young SP, Kautz MM, Albright A, et al

In addition to the rapid epigenetic modulation of glutamatergic function, preclinical studies showed that boosting mitochondrial metabolism of LAC protects against oxidative stress, rapidly ameliorates insulin resistance, and reduces neuroinflammation by decreasing proinflammatory pathways such as NFkB in hippocampal and cortical neurons
