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The column was washed with acetonitrile for 10 min followed by a linear gradient back to the initial mixture of 30% acetonitrile with the flow rate 1 ml/min

3.2 Luteolin inhibits GPVI-mediated platelet superoxide production, promotes SOD and GPx activity and impairs NOXs activity Collagen-bound platelet GPVI induces activation of NOXs, and NOXs activation mediates intracellular ROS release (Qiao et al., 2018

However, it is not enough only to have good structural characteristics, but also to induce bone formation

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