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Ontario Health Technology Assessment Series 2013;13:124

9 Getting a B12 Shot Earlier in the Day Will Decrease the Chance of Insomnia B12 shots do not contain any stimulants , but depending on how sensitive you are, getting the shot in the evening may lead to vivid dreams or insomnia

However, it is not recommended for use in newborns or premature infants, as neonates lack the metabolic capacity to process benzyl alcohol safely a contraindication explicitly noted in FDA guidance on benzyl alcohol toxicity in neonates

Injection Site Selection For subcutaneous injections, common sites include the abdomen at least two inches from the navel, front and outer thighs, and back of upper arms