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2 People assigned female at birth generally have a higher percentage of body fat, lower levels of water in the body, and less of the enzyme that breaks down alcohol, compared to people assigned male at birth

As an analog of endogenous growth hormone-releasing hormone (GHRH), tesamorelin boasts a metabolism-stimulating activity that has led to its being approved as a treatment for lipodystrophy, or abnormal adipose fat accumulation associated with antiretroviral therapy for HIV.3 But this same activity can help non-HIV individuals shed abdominal fat of their own, while the peptides GHRH properties make it a suitable therapy for people looking to increase their lean mass

Accessed February 17, 2025