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This inappropriate degranulation floods the surrounding tissues and bloodstream with a massive payload of inflammatory mediators, including histamine, tryptase, prostaglandins, and leukotrienes
Thus, mitochondrial destruction and associated kidney damage can be observed
[DOI] [PubMed] [Google Scholar] 32.Holmes J, Stanko J, Varchenko M, Ding H, Madden VJ, Bagnell CR, Wyrick SD, Chaney SG
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