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When traveling, the medication should be transported in an insulated container with ice packs if refrigeration will not be available, taking care to prevent direct contact between the medication and ice to avoid freezing

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The internal resistance also gradually increases throughout the lifetime of the battery due to chemical decay and acculumated damage from over-discharging
[DOI] [PubMed] [Google Scholar] 26.Moher D, Liberati A, Tetzlaff J, Altman DG
