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Description
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Role of astrocytes, microglia, and tanycytes in brain control of systemic metabolism

Addition of exogenous SOD1 aggregates causes TDP-43 mislocalisation and aggregation

This action may counter the aberrant glycolytic shift observed in immune cells, potentially alleviating T cell exhaustion and improving insulin sensitivity, leading to clinical trials assessing its impact on inflammation and comorbidities (156158)
