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Description
Novel ferroptosis inhibitors with improved potency and ADME properties
Another interesting class of carbon atoms that may serve as deuterium traps are the bis-allylic carbon atoms, notably present in both microbial breakdown products of haem and in polyunsaturated fatty acids (PUFAs)
The second raw enzyme is GSH synthetase (GSS), condensing the gamma-glutamyl-cysteine moiety with glycine, via a regular peptide bond
Our results identify specific druggable pathways that may lead to the design of effective therapeutic interventions for diverse forms of ASD
