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These guidelines focused on currently available endoscopic therapies for managing patients with chronic radiation proctopathy, which include argon plasma coagulation, bipolar electrocoagulation, heater probe, radiofrequency ablation, and cryoablation (66)

The K907A mutant IRE1 expression plasmid was generated through site-directed mutagenesis using the pLEX-hIRE1 plasmid (pLEX-hIRE1-K907A)

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