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Description
Aug 2014;21(8):886-9
The fact that monozygotic twins have similar epigenomes in their early years of life yet display significant changes in their epigenomes as they become older is proof that the epigenome is metastable and exhibits temporal variability
TFEB is the major transcription factor which activates genes that encode proteins involved in autophagy, lysosome biogenesis and mitochondrial biogenesis (Settembre et al., 2011, 2012
It can cause irritation
