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PINK1, as a mitochondrial damage sensor, is activated by mild oxidative stress and further triggers mitophagy to remove ROS and prevent cellular damage [167]

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DOI: 10.1001/jama.2013.280532

discovered the content of seven free anthraquinones and one combined anthraquinones in Juemingzi by HPLC-diode array detection (HPLC-DAD) ( Juemingzi has been used in East Asian countries (China, Japan, Korea.) for thousands of years to clear liver fire, which means relieving some symptoms of cardiovascular and cerebrovascular diseases and improving complications caused by hyperglycemia and hyperlipidemia