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Chronic in vivo GC effects on adipogenesis and white adipose tissue mass and distribution in humans: studies on Cushing syndrome By numerous potential mechanisms, including the production of proinflammatory cytokines and increased portal FA delivery to the liver, 34 abdominal obesity, the accumulation of visceral and trunk subcutaneous fat, is closely linked to the development of insulin resistance, dyslipidemia, and cardiovascular risk

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This chapter will refer to primary or acute effects as those effects that begin within the first minutes after injury, secondary or subacute effects as those that arise over the next 24 hours after injury, and long-term or chronic effects as those that are associated with the insult but occur at a later time

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