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Similarly, if Cu 2+ weakly bound to the sulfur atom of Met35 is the recipient of an electron from this S-atom to form the reduced Cu + (see above for discussion of a relatively weaker electron pair interaction with the S-atom protons in a polypeptide with -helical structure), this latter moiety can lead to the highly reactive hydroxyl free radical by Fenton chemistry as noted, initiating lipid peroxidation

Avoiding Common Reconstitution Pitfalls Over the years, we've compiled a list of common mistakes that can compromise research integrity

The precise mechanism underlying the cardiotoxicity remains elusive, potentially involving oxidative stress, apoptosis, aberrant expression of related genes, calcium overload, and the production of toxic metabolites (McGowan et al., 2017)

Technical Background Report for the Global Mercury Assessment 2013 Arctic Monitoring and Assessment Programme, Oslo, Norway/UNEP Chemicals Branch, Geneva, Switzerland