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A follow-up phase 2 study reported minimal adverse effects associated with this therapy (Stein et al., 2019), and there are several clinical trials further investigating this protein (NCT05234775, NCT04797247, NCT05004675, NCT03545438, NCT04034485, NCT04790513, NCT04806893, NCT04797104, NCT04798430, NCT03549260)