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Stronger causal evidence would require inhibitor, knockdown, rescue, or pathway-disruption experiments showing that interference with FAK signaling reduces or eliminates the BPC-157-associated migration response in the specific experimental system

The 14 peptides discussed above are not currently on that eligible list

The supplemental approval was granted based on data from the Phase III EMBARK trial, which studied Xtandi plus leuprolide, placebo plus leuprolide (a synthetic hormone regulator) and Xtandi as a monotherapy

These experimental systems often measure endpoints such as cellular migration capacity, collagen fiber organization, and biomechanical properties of healing connective tissue