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Under normoxic conditions, the TCA cycle proceeds oxidatively from pyruvate to citrate, succinate, fumarate, malate, and finally oxaloacetate

The pharmacodynamic action of curcumin is dose-dependent, typically requiring higher concentrations to achieve therapeutic efficacy

Encapsulating PTX in chitosan nanoparticles (CSNPs) could enhance its delivery by improving drug stability, prolonging circulation time, and enabling targeted release [34]

The operation was performed 339 days after diagnosis, revealing significant atrophy of the right liver and hypertrophy of the left lateral sector (Fig