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Its formulation includes the active pharmaceutical ingredient tirzepatide along with pharmaceutical excipients necessary for stability and delivery, but it does not contain any vitamins, including vitamin B12 (cobalamin)

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In the same trial, people on CagriSema lost an average of about 23% of their body weight over 68 weeks when measuring the effect assuming full adherence, or about 21% when accounting for all participants regardless of whether they completed treatment

Most of the time, this type of diet does not provide the daily amount of vitamin B12 required in the body, even if eggs, milk or dairy products are consumed occasionally