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The antianginal drug trimetazidine shifts cardiac energy metabolism from fatty acid oxidation to glucose oxidation by inhibiting mitochondrial long-chain 3-ketoacyl coenzyme A thiolase

However, large obesity trials did not show clinically meaningful weight loss, and regulators have raised concerns about immunogenicity and safety data gaps, which is why Better Med Spa restricts its use to clearly informed, highly selected clients

It is not approved for human or veterinary use, therapeutic applications, or diagnostic procedures

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