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Thereby, also for anti-glaucoma therapy with essential NO-importance [94], it may be quite indicative of the counteraction of the NO-synthase (NOS)-blocker effect, in particular, and thereby, counteraction of NO-system failure (i.e., retinal ischemia) supposedly particularly damaging for eye function [94,132,133,134,135,136]

Methionine synthase exists in two distinct conformations that differ in reactivity toward methyltetrahydrofolate, adenosylmethionine, and flavodoxin

Additionally, YYD has shown certain anti-inflammatory and antioxidant activities in vitro experiments or animal models, and through the regulation of tryptophan metabolism and glycerophospholipid metabolism, it can exert an improving effect on the pathological process of T2DM [155]