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Both topical and oral administration may be helpful
394 Mice fed a high iron diet as well as those with inherited hemochromatosis (Hjv / and Smad4 Alb/Alb mice) all developed systemic iron overload due to decreased hepcidin expression in liver
In addition, delayed tumor growth of Fads-knockdown cells in both immune-deficient and immune-competent mice suggests a direct inhibitory effect of FADS loss on HCC cell growth in vivo
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