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Hepatic glutathione homeostasis in the rat: Efflux accounts for glutathione turnover
However, increased ROS production in PD is closely linked to mitochondrial dysfunction (Weng et al., 2018) The discovery that mutations in the genes encoding proteins like -syn, parkin, DJ-1, or PINK are associated with familial types of PD raises the question of how oxidative stress and dopamine (DA) cell damage are related to mitochondrial dysfunction (Gonchar et al., 2019
In chronic alcohol use, sustained acetaldehyde accumulation exposes hepatocytes to toxic concentrations
Environ Sci Pollut Res 31:4765547673
