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The two segments on the human CENP-C (CENP-C 426537 and CENP-C 737-359 ) recognize and bind the CENP-A nucleosome by interlocking with its C-terminal tail, which is exposed on the surface of the nucleosome and the acidic patch on histone H2A that is also exposed on the surface of the nucleosome

BPC 157 also has an effect on blood vessels, resulting in vessel recruitment that circumvents vessel occlusion and the development of additional shunting and rapid bypass loops to rapidly reestablish the integrity of blood flow (ischemic/reperfusion colitis, duodenal lesions, cecal perforation, and inferior vena caval occlusion)

[Vitamin C and prevention of reflex sympathetic dystrophy following surgical management of distal radius fractures]