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An antibody that blocks LINGO-1, opicinumab, has shown promise and is being tested in proof-of-concept trials by Biogen

Preclinical research has shown that chemotherapeutic agents such as oxaliplatin, paclitaxel, cyclophosphamide, methotrexate, 5-fluorouracil or doxorubicin can induce short- and long-term deleterious effects in working memory and fear and spatial learning in a wide variety of rodent models (Table 1)

Verification: Live search confirms that human plasma concentrations of GHK-Cu drop by over 60% during a standard human lifespan, falling from approximately 200 ng/mL at age 20 to 80 ng/mL by age 60

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